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MYP_173949
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Basic Information
UyCT3
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
13 amino acids
C70H111N15O17
Standard
Sequence
ILSAIWSGIKSLF
Physicochemical Analysis
1434.72 Da
8.75
0.76
0.55
0.0584
1.39
0.51
0.56
10.98
157.69
0.1538
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
515.02
-1.83
19.0
18.0
46.0
102.0
3.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0029022 VERIFIED: YES
Provenance & Taxonomy
Urodacus yaschenkoi [Animal] [Animal]; Opisthacanthus cayaporum [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
15 μM
MIC
RECORD: Rec_0029753 VERIFIED: YES
Provenance & Taxonomy
Urodacus yaschenkoi [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Cryptococcus neoformans B3501 serotype D
12.5 μM
MIC
PaperCharacterization of the venom from the Australian scorpion Urodacus yaschenkoi: Molecular mass analysis of components, cDNA sequences and peptides with antimicrobial activity
RECORD: Rec_0030063 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0048086 VERIFIED: YES
Provenance & Taxonomy
Urodacus yaschenkoi [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli
6-15 μM
MIC
PaperCharacterization of the venom from the Australian scorpion Urodacus yaschenkoi: Molecular mass analysis of components, cDNA sequences and peptides with antimicrobial activity
RECORD: Rec_0099578 VERIFIED: YES
Provenance & Taxonomy
Urodacus yaschenkoi [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
PaperPubMed PMID: 23182832 PMID23182832 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23182832/
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