MYP_173912
Potassium channel toxin alpha-KTx 6.13
Annotation / Sequence feature
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Nuclear export signal
Anticancer
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Cytotoxic anticancer activity
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Cytotoxic
Immunology
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Innate immune defense
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Host defense peptide
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Host defense activity
Membrane / Ion-channel modulation
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Ion channel inhibition
Membrane / Ion-channel modulation
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Ion channel modulation
Membrane / Ion-channel modulation
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Potassium channel modulation
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Potassium channel inhibitor
Toxicity / Safety
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Cytotoxicity
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Cytotoxic
Venom / Toxin
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General toxin
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Cytotoxic
Venom / Toxin
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General toxin
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Toxic
Venom / Toxin
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General toxin
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Toxin
Venom / Toxin
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Toxin
Standard
34 amino acids
C147H243N47O47S9
Standard
IRCSGSRDCYSPCMKQTGCPNAKCINKSCKCYGC
3709.37 Da
8.91
4.68
4.35
0.1375
-0.49
0.56
-0.19
59.84
25.88
0.0588
2980.00
3480.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1542.10
-22.61
62.0
61.0
122.0
250.0
4.0
36.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0008663
VERIFIED: YES
Provenance & Taxonomy
Heterometrus spinifer [Animal]
Potassium channel inhibitor family
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
3-24; 9-29; 13-31; 19-34
Bio-Activity Profile
Toxin
Venom
Potassium channel inhibitor family
Ion channel inhibitor
Pathogenesis-associated
Host defense
RECORD: Rec_0020431
VERIFIED: NO
Provenance & Taxonomy
Heterometrus spinifer [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Toxin
Channel blocker
Kv1
RECORD: Rec_0229270
VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Toxic
Cytotoxic