Peptide Database

Peptide NameSperm-associated antigen 11 variant C isoform 1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length133 amino acids

Chemical FormulaC657H1022N184O185S8

DescriptionStandard

        MKRRLLPSFVSLLLAALLLPGKAETWLRSWTQALSAGVTLGSSSASSINHLVTEPPSSPQDEFPAQGGNGSGLLHHRVKRFPPRTPPYHEPGPNYQIVNCKKNEGFCQKYCNFMETQVGYCSKKKEACCLHPF
    

Molecular Weight14714.78 Da

Isoelectric Point (pI)9.28

Net Charge (pH 7.0)6.88

Net Charge (pH 7.4) 6.30

Charge Density (pH 7.0) 0.0518

GRAVY Index-0.40

Hydrophobic Moment 0.66

Boman Index0.00

Instability Index51.21

Aliphatic Index 68.95

Aromaticity 0.0902

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 17335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5851.58

LogP -60.92

H-bond Donors 204.0

H-bond Acceptors 205.0

Rotatable Bonds 470.0

Heavy Atoms 1034.0

Ring Count 32.0

Amide Bonds 144.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0215360 VERIFIED: NO

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyDefensin

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

PaperCross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract PMID16033865 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16033865/; https://www.uniprot.org/uniprotkb/Q30KI9/entry; https://bblserver.org.in/ampdb/