Peptide Database

Peptide NameColicin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length176 amino acids

Chemical FormulaC810H1313N217O243S5

DescriptionStandard

        MGIAVSGEALSAAIADIFAALKGPFKFSAWGIALYGILPSEIAKDDPNMMSKIVTSLPAETVTNVQVSTLPLDQATVSVTKRVTDVVKDTRQHIAVVAGVPMSVPVVNAKPTRTPGVFHASFPGVPSLTVSTVKGLPVSTTLPRGITEDKGRTAVPAGFTFGGGSHEAGTRCPKES
    

Molecular Weight18139.72 Da

Isoelectric Point (pI)9.17

Net Charge (pH 7.0)2.77

Net Charge (pH 7.4) 2.35

Charge Density (pH 7.0) 0.0157

GRAVY Index0.20

Hydrophobic Moment 0.69

Boman Index0.17

Instability Index33.80

Aliphatic Index 89.15

Aromaticity 0.0511

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7188.66

LogP -84.79

H-bond Donors 248.0

H-bond Acceptors 254.0

Rotatable Bonds 577.0

Heavy Atoms 1275.0

Ring Count 28.0

Amide Bonds 181.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0400585 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyPyocin/Colicin

Tax ID562

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic Non-ribosomal

TargetEscherichia coli