Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length527 amino acids

Chemical FormulaC2687H4212N690O772S23

DescriptionStandard

        MMARPHCVVVVLLLLAVVSGLKEGASNPGFVARITRKGLEYARQYGVAILKKELSTIELPDFSGSFEVSWIKIMSYEFYRLKIHDFELRNSDLRLCPRQGVRASLSNNYVTVSGNWKIKKAFFSFKGTFYMKVDDICISAFLNLGKDQSGRLTASMAHCNNSIGHISIDISGKLSWILNLFHERIENKFKNILEQKICEMVEKATTSRLEPYLQTLPVISMIDQVASIDYSLIGAPQVTSQVLDTPFKGEFFGQNGHSRAPFDAPPIRLPEKHDYMVYFAISEYVFNTASWVYHQAGYMNFTIQNQHMQNLTKLASKPSAEKWREQYLGSTCLTSNSALLTTSCISSSLLLLLQISPDSPIYLHTSSFPALVPQLARMYPNMELELEMSPESAPLLMFTPGNVTLMPVIDVQAFALKPNSSDRKPLFQLRVTTSISATINVSSDRIVGSVTPGSKLKLELKHSNINFIDVELMEVILNYYALHTIYPSLNAKLEEGFPLPLPVDTYLNSSELQVHENFLLLVANLDY
    

Molecular Weight59271.84 Da

Isoelectric Point (pI)6.90

Net Charge (pH 7.0)-0.38

Net Charge (pH 7.4) -1.49

Charge Density (pH 7.0) -0.0007

GRAVY Index0.01

Hydrophobic Moment 0.84

Boman Index0.11

Instability Index36.47

Aliphatic Index 98.60

Aromaticity 0.0987

Extinction Coeff. Reduced 58790.00

Extinction Coeff. Oxidized 59165.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0341047 VERIFIED: NO

Provenance & Taxonomy

OrganismNyctereutes procyonoides (Raccoon dog) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria