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MYP_173849
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Basic Information
N-1 (analog of P18)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
17 amino acids
C112H174N26O18
Standard
Sequence
WKLFKKIPKFLHLAKKF
Physicochemical Analysis
2172.74 Da
10.70
5.84
5.58
0.3436
-0.18
0.82
0.02
-11.11
97.65
0.2353
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
720.72
2.06
25.0
25.0
74.0
156.0
7.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0007783 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Gaegurin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
human red blood cells
100 μg/mL
Hemolysis
PMID12005420 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12005420/
RECORD: Rec_0008595 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Gaegurin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa KCTC 1637
1.56 μM
MIC
PMID12005420 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12005420/
RECORD: Rec_0051668 VERIFIED: YES
Provenance & Taxonomy
Insecta [Animal]
50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PMID12005420 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12005420/
RECORD: Rec_0058206 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
CA-MA / CA-ME hybrid peptide family
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
RECORD: Rec_0079257 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Gaegurin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus KCTC 1621
3.125 μM
MIC
PMID12005420 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12005420/
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