Peptide Database

Peptide NameUnnamed

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Standard StatusStandard

Sequence Length8 amino acids

Chemical FormulaC53H72N16O14

DescriptionStandard

        THDWWKER
    

Molecular Weight1157.24 Da

Isoelectric Point (pI)6.42

Net Charge (pH 7.0)-0.51

Net Charge (pH 7.4) -0.76

Charge Density (pH 7.0) -0.0640

GRAVY Index-2.64

Hydrophobic Moment 0.13

Boman Index-0.56

Instability Index8.75

Aliphatic Index 0.00

Aromaticity 0.2500

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 510.03

LogP -2.68

H-bond Donors 19.0

H-bond Acceptors 15.0

Rotatable Bonds 35.0

Heavy Atoms 83.0

Ring Count 5.0

Amide Bonds 7.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0337362 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antihypertensive ACE inhibitory

TargetAngiotensin-converting enzyme (ACE)

Activity583.6

MethodIC50