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MYP_173834
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Basic Information
LL-37 (15-32)[Q8K,D12K,N16K]
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
18 amino acids
C111H197N33O21
Standard
Sequence
KEFKRIVKRIKKFLRKLV
Physicochemical Analysis
2329.96 Da
11.76
7.76
7.54
0.4309
-0.54
1.07
-0.44
32.27
118.89
0.1111
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
937.14
-2.95
35.0
29.0
88.0
165.0
2.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0219581 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Murine macrophage cells RAW 264.7
PMID21790937;23689720 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21790937/
RECORD: Rec_0234177 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Natural peptide
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antimycobacterial
Mycobacterium smegmatis mc2 155
MIC
PMID21790937 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21790937/
RECORD: Rec_0244738 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Mycobacterium smegmatis mc2-155 90-100% Killing
25 μg/mL
PMID21790937;23689720 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21790937/
RECORD: Rec_0306808 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Cathelicidin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antimycobacterial Immunomodulatory
Mycobacterium tuberculosis H37Rv
MIC
PMID25613372 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25613372/
RECORD: Rec_0326426 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Murine macrophage cells J774A.1 - at NA
774
Hemolysis
PMID21790937;23689720 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21790937/
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