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MYP_173768
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Basic Information
Dermaseptin-PC (1-19), DM-PC (1-19)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
19 amino acids
C92H159N25O22
Standard
Sequence
ALWKSILKNVGKAAGKAVL
Physicochemical Analysis
1967.40 Da
10.48
3.79
3.60
0.1996
0.52
0.68
0.21
14.20
133.68
0.0526
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
770.31
-4.93
27.0
26.0
68.0
139.0
2.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0318928 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC BAA-3051
31.3 μg/mL
MIC
PMID31653005 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31653005/
RECORD: Rec_0318938 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 12493
8 μM
MIC
PMID31653005 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31653005/
RECORD: Rec_0337907 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Horse erythrocytes
64 μM
Hemolysis
PMID31653005 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31653005/
RECORD: Rec_0346312 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Enterococcus faecalis ATCC 29212
250 μg/mL
MBC
PMID31653005 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31653005/
RECORD: Rec_0348252 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa
64 μM
MIC
PMID31653005 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31653005/
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