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MYP_173768
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Basic Information
Dermaseptin-PC (1-19), DM-PC (1-19)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
19 amino acids
C92H159N25O22
Standard
Sequence
ALWKSILKNVGKAAGKAVL
Physicochemical Analysis
1967.40 Da
10.48
3.79
3.60
0.1996
0.52
0.68
0.21
14.20
133.68
0.0526
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
770.31
-4.93
27.0
26.0
68.0
139.0
2.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0053412 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus
PMID31653005 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31653005/
RECORD: Rec_0060726 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus NCTC 10788
8 μM
MBC
PMID31653005 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31653005/
RECORD: Rec_0078057 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa ATCC 27853
4 μM
MIC
PMID31653005 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31653005/
RECORD: Rec_0119260 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Cytotoxic
Human embryonic kidney HEK293 cells
125 μg/mL
Cytotoxicity
PMID31653005 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31653005/
RECORD: Rec_0140346 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC BAA-3051
31.3 μg/mL
MBC
PMID31653005 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31653005/
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