Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length443 amino acids

Chemical FormulaC2237H3534N618O622S15

DescriptionStandard

        TNPGFVVRITQAGLDYAHQHGITILEKELAQLRLPDMSGDFRVLRVGKVRYELSRLRLRSFHLPYSRISPVPNVGLQVSISNAFAELDGDWRVKMLFVRDHGSFDLKVENVYIKISLRLGSDTTGKPTVSTSDCSTRISKVRVLFSGKFGWLYNLFHSAIESKFRKILEGKVCDSIAESVHNDLQTYTRTLPVTARIDARTGIDYSFVAPPYATAQSLDTGLKGEFYNLAHRSTVPFSPLPLSLPSDHDRMVYFGASNYFFNTAGFAYHEAGALVFEITNAMVFSPRSSVLCCCAHPLPVPMQLEQMYPDMPMKLRLSTPSAPFLNIGPEGISLRPVVDVQAYAILPNSSLAPLFLLSLVRNVSAVIDVRSGRIVGSLDVGRYRGEQLLLGRGRWGVRMLQSIMNIFASDILLPRLNARLEKGFPLPLPDRIRLSNTLVRFHQ
    

Molecular Weight49518.73 Da

Isoelectric Point (pI)9.57

Net Charge (pH 7.0)13.35

Net Charge (pH 7.4) 12.44

Charge Density (pH 7.0) 0.0301

GRAVY Index0.01

Hydrophobic Moment 0.76

Boman Index0.06

Instability Index41.04

Aliphatic Index 98.33

Aromaticity 0.0948

Extinction Coeff. Reduced 38850.00

Extinction Coeff. Oxidized 39100.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0237863 VERIFIED: NO

Provenance & Taxonomy

OrganismXiphorhynchus elegans [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria