Peptide Database

Peptide NameAlyteserin-2a [T8W]

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC79H133N19O20

DescriptionStandard

        ILGKLLSWAAGLLSNL
    

Molecular Weight1669.02 Da

Isoelectric Point (pI)8.75

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.55

Charge Density (pH 7.0) 0.0474

GRAVY Index1.26

Hydrophobic Moment 0.37

Boman Index0.51

Instability Index1.41

Aliphatic Index 183.12

Aromaticity 0.0625

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 625.18

LogP -2.99

H-bond Donors 22.0

H-bond Acceptors 21.0

Rotatable Bonds 55.0

Heavy Atoms 118.0

Ring Count 2.0

Amide Bonds 16.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0035742 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

FamilyAlyteserin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Anticancer Cytotoxic

RECORD: Rec_0148259 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

FamilyAlyteserin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetTumor cells: A549

Activity12 μM

MethodLC50

RECORD: Rec_0177787 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

FamilyAlyteserin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Anticancer Hemolytic

TargetHuman erythrocytes

Activity13 μM

MethodHemolysis

RECORD: Rec_0313892 VERIFIED: YES

Provenance & Taxonomy

OrganismAlytes obstetricans [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Cell-penetrating peptide

TargetHuman erythrocytes

Activity13 μM

MethodLC50

RECORD: Rec_0379514 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Toxic Drug Delivery Vehicle Cell-penetrating peptide Hemolytic