Peptide Database

Peptide NameSLAY-screened peptide P3480

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC103H162N28O30S2

DescriptionStandard

        TSFANSHRPLYILPMICTASN
    

Molecular Weight2336.69 Da

Isoelectric Point (pI)7.92

Net Charge (pH 7.0)0.47

Net Charge (pH 7.4) 0.22

Charge Density (pH 7.0) 0.0226

GRAVY Index0.21

Hydrophobic Moment 0.41

Boman Index0.17

Instability Index48.97

Aliphatic Index 83.81

Aromaticity 0.0952

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 925.88

LogP -10.08

H-bond Donors 33.0

H-bond Acceptors 34.0

Rotatable Bonds 70.0

Heavy Atoms 163.0

Ring Count 5.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0392742 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/