Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length782 amino acids

Chemical FormulaC3901H6204N1006O1113S32

DescriptionStandard

        RELLLSGQTEKQRQRVKVLRQRCKVRLNMVSLWCVLALLTFLSPEASGTNPGVKVRLTEKGLEYGRQIGLIALQQKLKDIKIPDISGSEKVSPIGKVSYSLTGIKIVNLGLPKSAVGLVPGTGVSLSIGDAYINLHGNWRVKYMKIIKDSGSFDLSVSGLSISATIGVKDDGAGRPMVGCAACEDSVGHVSVKFHGGASWLYNLFKNYVDNALRKALQTQICPLVGEAIQEMNPHLKTLNVLAQVDKYAEIEYSMMESPLISNSSIDLSLKGEFYNIGHHTEPPFAPTPFSLPPQDSNMLYMALSAFTMNSAGFVYNIAGVLGLYVTDDMIPSSFPFRLNTKTFGTFIPEIAKQYPGLMMKLLVKAVKEPHVTFETNNVMMEANSTITAYAIQPNATLTPLFILNVNASVSAQIYITGLNLAGVLSLNEMDMTLGTSYVGPFQVKSLDNVLSLVLKGVVIPTVNAYLKQGYPLPAIGKMNLVNTQLQILKVRVNMVSLWCVLALFTFLFLETSGTNPGVRIRITQKGLEYQRQISISPLVEKLKSIHVPNRSGSGHILFMDIYYAVKNWLYELFDGFIDSILRNALQSQGMFYNIGNHTEPPFSPTPFSLPHQDNKMLYMALSAFTLNSASFVYNNARVLNQYITDNMIPSGSSFRLETKTFGTLIPQIAKQYPGLKMKLLVKAVEEPHFSFETNNVTMQASSTVTAYAVQPNAPLTPLFVLNLNASVSARIYIKDLKVAGNVTLNKIDMTLRTSNVGPFQVELLDNAFKTVLNVALIPEVN
    

Molecular Weight86031.14 Da

Isoelectric Point (pI)9.16

Net Charge (pH 7.0)14.78

Net Charge (pH 7.4) 13.71

Charge Density (pH 7.0) 0.0189

GRAVY Index0.12

Hydrophobic Moment 0.68

Boman Index0.15

Instability Index34.29

Aliphatic Index 102.56

Aromaticity 0.0870

Extinction Coeff. Reduced 70710.00

Extinction Coeff. Oxidized 71085.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0257057 VERIFIED: NO

Provenance & Taxonomy

OrganismClarias magur [Animal]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic Non-ribosomal

TargetGram-negative bacteria

MethodQualitative functional evidence