Peptide Database

Peptide NamepAntp (43-48)

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length6 amino acids

Chemical FormulaC40H66N12O8

DescriptionStandard

        RQIKIW
    

Molecular Weight843.03 Da

Isoelectric Point (pI)11.00

Net Charge (pH 7.0)1.76

Net Charge (pH 7.4) 1.55

Charge Density (pH 7.0) 0.2932

GRAVY Index-0.63

Hydrophobic Moment 0.70

Boman Index-0.22

Instability Index12.13

Aliphatic Index 130.00

Aromaticity 0.1667

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 355.62

LogP -0.70

H-bond Donors 13.0

H-bond Acceptors 10.0

Rotatable Bonds 28.0

Heavy Atoms 60.0

Ring Count 2.0

Amide Bonds 6.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0391975 VERIFIED: YES

Provenance & Taxonomy

OrganismDrosophila melanogaster [Animal]

FamilyPenetratin

Tax ID7227

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermBiotinylation

C-TermAmidation

Other ModsN-term detail: Labeled with Biotinyl-bAla

Bio-Activity Profile

Function

Cell-penetrating peptide

TargetHaCat/ A549 cells

MethodCellular uptake assay

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