Peptide Database

Peptide NameC-X-C motif chemokine 6 (Chemokine alpha 3) (CKA-3) (Granulocyte chemotactic protein 2) (GCP-2) (Small-inducible cytokine B6) [Cleaved into: Small-inducible cytokine B6; N-processed variant 1; Small-inducible cytokine B6; N-processed variant 2; Small-inducible cytokine B6; N-processed variant 3]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Immune cell migration ▸ Chemotactic peptide

Immunology ▸ Immune modulation ▸ Cytokine modulation

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC530H905N147O148S6

DescriptionStandard

        MSLPSSRAARVPGPSGSLCALLALLLLLTPPGPLASAGPVSAVLTELRCTCLRVTLRVNPKTIGKLQVFPAGPQCSKVEVVASLKNGKQVCLDPEAPFLKKVIQKILDSGNKKN
    

Molecular Weight11897.14 Da

Isoelectric Point (pI)9.91

Net Charge (pH 7.0)9.45

Net Charge (pH 7.4) 9.14

Charge Density (pH 7.0) 0.0829

GRAVY Index0.25

Hydrophobic Moment 0.74

Boman Index0.10

Instability Index49.64

Aliphatic Index 112.02

Aromaticity 0.0175

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4650.51

LogP -46.84

H-bond Donors 161.0

H-bond Acceptors 164.0

Rotatable Bonds 390.0

Heavy Atoms 831.0

Ring Count 14.0

Amide Bonds 121.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0172931 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyIntercrine alpha (chemokine CxC)

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Cytokine Chemotactic Non-hemolytic

TargetGram Negative Bacteria and Gram Positive Bacteria