Peptide Database

Peptide NameLeumorphin

Function Ontology

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC158H230N42O48

DescriptionStandard

        YGGFLRRQFKVVTRSQEDPNAYSEEFFDV
    

Molecular Weight3485.77 Da

Isoelectric Point (pI)4.94

Net Charge (pH 7.0)-1.23

Net Charge (pH 7.4) -1.45

Charge Density (pH 7.0) -0.0425

GRAVY Index-0.80

Hydrophobic Moment 0.82

Boman Index-0.16

Instability Index87.59

Aliphatic Index 46.90

Aromaticity 0.2069

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1497.97

LogP -14.12

H-bond Donors 52.0

H-bond Acceptors 47.0

Rotatable Bonds 113.0

Heavy Atoms 248.0

Ring Count 7.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0089217 VERIFIED: YES

Provenance & Taxonomy

OrganismCavia porcellus [Animal]

FamilyLeumorphin

Tax ID10141

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide Neuromodulator

Half-LifeMammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min

RECORD: Rec_0246598 VERIFIED: NO

Provenance & Taxonomy

OrganismCavia porcellus [Animal]

FamilyOpioid

Tax ID10141

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Opioid Analgesic Neuromodulator

RECORD: Rec_0333977 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/