Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length153 amino acids

Chemical FormulaC796H1240N208O239S12

DescriptionStandard

        MNLLMLTFMLCGLLTLVTKAGWFVERCWKNDIGYCRKRCLLLERYKLLCVNKQSCCIPLRSYDPYTQWPIHRTFFKDLNVEYITHDDFPFSPDSGFTDEVTVKATMTQESRTLTPTPESTKDTTFSDEPETLETTTPTTNTYLTRQRRKSDMP
    

Molecular Weight17932.39 Da

Isoelectric Point (pI)6.71

Net Charge (pH 7.0)-0.37

Net Charge (pH 7.4) -0.84

Charge Density (pH 7.0) -0.0024

GRAVY Index-0.49

Hydrophobic Moment 0.59

Boman Index-0.08

Instability Index45.97

Aliphatic Index 66.21

Aromaticity 0.1111

Extinction Coeff. Reduced 25440.00

Extinction Coeff. Oxidized 25815.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7221.78

LogP -69.53

H-bond Donors 261.0

H-bond Acceptors 253.0

Rotatable Bonds 580.0

Heavy Atoms 1255.0

Ring Count 32.0

Amide Bonds 161.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0056955 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyDefensin

Tax ID9913

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0083623 VERIFIED: NO