Peptide Database

Peptide NameDefb14-1CV(14-23)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length10 amino acids

Chemical FormulaC40H73N17O12

DescriptionStandard

        RGGRAAVLNA
    

Molecular Weight984.11 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)1.76

Net Charge (pH 7.4) 1.56

Charge Density (pH 7.0) 0.1760

GRAVY Index0.01

Hydrophobic Moment 0.48

Boman Index-0.09

Instability Index12.85

Aliphatic Index 98.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 492.11

LogP -6.81

H-bond Donors 18.0

H-bond Acceptors 14.0

Rotatable Bonds 32.0

Heavy Atoms 69.0

Ring Count 0.0

Amide Bonds 10.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0144554 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetMonomer: [Pseudomonas aeruginosa PAO1

Activity48 μM

MethodMIC