Peptide Database

Peptide NameWN53

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antiviral

Antiviral ▸ Anti-Flavivirus ▸ Anti-West Nile virus

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC142H203N37O36S

DescriptionStandard

        TFLVHREWFMDLNLPWSSAGSTVWR
    

Molecular Weight3036.42 Da

Isoelectric Point (pI)6.42

Net Charge (pH 7.0)-0.51

Net Charge (pH 7.4) -0.75

Charge Density (pH 7.0) -0.0204

GRAVY Index-0.08

Hydrophobic Moment 0.50

Boman Index0.14

Instability Index22.78

Aliphatic Index 74.00

Aromaticity 0.2000

Extinction Coeff. Reduced 16500.00

Extinction Coeff. Oxidized 16500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1171.62

LogP -7.50

H-bond Donors 43.0

H-bond Acceptors 38.0

Rotatable Bonds 91.0

Heavy Atoms 216.0

Ring Count 10.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0425616 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilySynthetic peptide

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Entry inhibitor

TargetWest Nile virus (Virus entry); LLC-MK2

Activity56 %

MethodPlaque assay

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