Peptide Database

Peptide NameBeta-defensin 126

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length112 amino acids

Chemical FormulaC525H871N145O156S13

DescriptionStandard

        MKSLLFTLAVFMLLAQLVSGNWYVKKCLNDVGICKKKCKPEELHVKNGRAMCGKQRDCCVPADKRANYPAFCVQTKTTRTSTVTATAATTTTLVMTTASMSSMAPTPVSPTS
    

Molecular Weight12127.25 Da

Isoelectric Point (pI)9.56

Net Charge (pH 7.0)9.51

Net Charge (pH 7.4) 9.12

Charge Density (pH 7.0) 0.0849

GRAVY Index-0.01

Hydrophobic Moment 0.46

Boman Index0.03

Instability Index31.12

Aliphatic Index 70.54

Aromaticity 0.0536

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4833.08

LogP -55.69

H-bond Donors 177.0

H-bond Acceptors 180.0

Rotatable Bonds 399.0

Heavy Atoms 839.0

Ring Count 14.0

Amide Bonds 118.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0112294 VERIFIED: NO

Provenance & Taxonomy

OrganismHylobates lar [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence