Peptide Database

Peptide NameEC-proHep3

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC158H223N51O41S4

DescriptionStandard

        APAKCTPYCYPTRDGVFCGVRCDFQHHHHHH
    

Molecular Weight3621.04 Da

Isoelectric Point (pI)7.96

Net Charge (pH 7.0)1.28

Net Charge (pH 7.4) 0.72

Charge Density (pH 7.0) 0.0412

GRAVY Index-0.79

Hydrophobic Moment 0.41

Boman Index-0.09

Instability Index40.38

Aliphatic Index 25.16

Aromaticity 0.1290

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1430.46

LogP -14.40

H-bond Donors 53.0

H-bond Acceptors 52.0

Rotatable Bonds 105.0

Heavy Atoms 254.0

Ring Count 13.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0000543 VERIFIED: YES

Provenance & Taxonomy

OrganismEpinephelus coioides [Animal]

FamilyHepcidin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetP. fluorescens

Activity24.48 μM

MethodMIC

RECORD: Rec_0044420 VERIFIED: YES

Provenance & Taxonomy

OrganismEpinephelus coioides [Animal]

FamilyHepcidin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli

Activity96 μM

MethodMIC

RECORD: Rec_0055900 VERIFIED: YES

Provenance & Taxonomy

OrganismEpinephelus coioides [Animal]

FamilyHepcidin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetShigella flexineri

Activity96 μM

MethodMIC

RECORD: Rec_0068641 VERIFIED: YES

Provenance & Taxonomy

OrganismEpinephelus coioides [Animal]

FamilyHepcidin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetVibrio harvryi

Activity96 μM

MethodMIC

RECORD: Rec_0079859 VERIFIED: YES

Provenance & Taxonomy

OrganismEpinephelus coioides [Animal]

FamilyHepcidin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetVibrio fluvialis

Activity96 μM

MethodMIC

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