Peptide Database

Peptide NameSLAY-screened peptide P2717

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC104H150N28O31S

DescriptionStandard

        SFFHASLTEHYCTHQLSLAQ
    

Molecular Weight2320.54 Da

Isoelectric Point (pI)6.19

Net Charge (pH 7.0)-1.29

Net Charge (pH 7.4) -1.66

Charge Density (pH 7.0) -0.0643

GRAVY Index-0.10

Hydrophobic Moment 0.16

Boman Index0.15

Instability Index53.63

Aliphatic Index 68.50

Aromaticity 0.1500

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 947.12

LogP -9.82

H-bond Donors 34.0

H-bond Acceptors 34.0

Rotatable Bonds 72.0

Heavy Atoms 164.0

Ring Count 6.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0112510 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/