Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length187 amino acids

Chemical FormulaC924H1489N255O251S9

DescriptionStandard

        PTALPTAHEPMLLLAVTEFVANSAAFVYYTAGALRRNISSNMLPRRFPLQLTTKSLGVFCPQLQERYPDQPMELHLSARRQPLLSCRPDALHGALFSSTEAFVVLPNATRVPAFLLNIDVNVTGKPTITGNRLGGTVSMKGPLCLRRTGLSGLPVLQVKKLETLLKFVLWLFGVPRANSECCPHTVP
    

Molecular Weight20474.85 Da

Isoelectric Point (pI)9.82

Net Charge (pH 7.0)9.27

Net Charge (pH 7.4) 8.91

Charge Density (pH 7.0) 0.0496

GRAVY Index0.14

Hydrophobic Moment 0.59

Boman Index0.11

Instability Index56.64

Aliphatic Index 100.11

Aromaticity 0.0695

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10220.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7966.76

LogP -95.39

H-bond Donors 279.0

H-bond Acceptors 273.0

Rotatable Bonds 651.0

Heavy Atoms 1439.0

Ring Count 36.0

Amide Bonds 200.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0030674 VERIFIED: NO

Provenance & Taxonomy

OrganismPsophia crepitans [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria