Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC375H635N95O108S8

DescriptionStandard

        MKLLLLLLTVTLLLAQVTPVMKCWGKSGRCRTTCKKTEVYYILCKTEAKCCVDPKYVPVKSKLTDTNTSLESTSAV
    

Molecular Weight8459.15 Da

Isoelectric Point (pI)9.28

Net Charge (pH 7.0)6.44

Net Charge (pH 7.4) 6.11

Charge Density (pH 7.0) 0.0847

GRAVY Index0.17

Hydrophobic Moment 0.62

Boman Index0.04

Instability Index14.99

Aliphatic Index 101.18

Aromaticity 0.0526

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3276.29

LogP -29.25

H-bond Donors 123.0

H-bond Acceptors 123.0

Rotatable Bonds 284.0

Heavy Atoms 586.0

Ring Count 8.0

Amide Bonds 77.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0313068 VERIFIED: NO

Provenance & Taxonomy

OrganismChlorocebus sabaeus [Animal]

FamilyBeta-defensin; Defensin

Tax ID60711

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic

RECORD: Rec_0417893 VERIFIED: NO