Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length594 amino acids

Chemical FormulaC2968H4721N799O838S21

DescriptionStandard

        MARGPDSARRWATLVVLATLGTAVTTTTNPGIVARVTQKGLDYACQQGVVTLQKELEKITIPTFSGSFKIKYLGKGQYCFSSMVIQGFSLPNSQIRPSPGEGLDLAIRDASINIRGKWKARKNFIKLSGKFDLSVEGISILAGLKLGYDPDSGHSTVTCSNCSSHINTVRIRISGSRLGWLIQLFHKRIESSLQNAMTSKICEVVTSTVSSKLQPYFETLPVTTKLDKVAGVDYSLVAPPRATTDNLDGLLKGEFFSLAHRSPPPFAPPPMAFPADHDRMVYLGISEYFFNTAGFVYQEAGALNLTLRDDMIPKESKFRLTTKFFGTLIPQVAKMFPDMQMQLFIWASLPPKLTVNASGLDLIFVLDTQAFAILPNSSLDPLFQLEMNLNLSVHLGAKSDRLIGELRLDKLLLELKHSDIGPFSVELLQSVMNYVMPTIVLPAINRKLQKGFPLPLPAYIELYNLVLQPYQHGVSATGPPKKFLPGHFHQQKHNSHLSVTRPRFQSLSCAQRIHAGYLSVSTLKLLRPTMSQRADNSTRKPSPTLAFLTSVQGFLTTLMGNPHPDSSLSLTSNIQSISPQFFCPNRRTPKTKRQ
    

Molecular Weight65678.45 Da

Isoelectric Point (pI)9.72

Net Charge (pH 7.0)24.67

Net Charge (pH 7.4) 23.53

Charge Density (pH 7.0) 0.0415

GRAVY Index-0.08

Hydrophobic Moment 0.69

Boman Index0.07

Instability Index39.56

Aliphatic Index 92.26

Aromaticity 0.0842

Extinction Coeff. Reduced 42860.00

Extinction Coeff. Oxidized 43235.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0364936 VERIFIED: NO

Provenance & Taxonomy

OrganismOdocoileus virginianus texanus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria