Peptide Database

Peptide NameDefensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC385H613N113O104S10

DescriptionStandard

        MAKFAGSIALEVLFLVVAQFEEITMRVEARTCQRASQTWKGVCFRNEKCRNNCLREKARTGNCKYVFRACICYFPC
    

Molecular Weight8809.33 Da

Isoelectric Point (pI)9.22

Net Charge (pH 7.0)6.43

Net Charge (pH 7.4) 6.08

Charge Density (pH 7.0) 0.0846

GRAVY Index-0.04

Hydrophobic Moment 0.68

Boman Index-0.07

Instability Index27.43

Aliphatic Index 69.34

Aromaticity 0.1184

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3565.39

LogP -33.66

H-bond Donors 135.0

H-bond Acceptors 121.0

Rotatable Bonds 295.0

Heavy Atoms 612.0

Ring Count 11.0

Amide Bonds 82.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0131175 VERIFIED: YES

Provenance & Taxonomy

OrganismTrichosanthes kirilowii [Plant]

FamilyDefensin

Tax ID3677

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Non-hemolytic Non-ribosomal