Peptide Database

Peptide NameProtein CLAVATA 3

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length75 amino acids

Chemical FormulaC361H576N114O108S5

DescriptionStandard

        SDLTQAHAHVQGLSNRKMMMMKMESEWVGANGEAEKAKTKGLGLHEELRTVPSGPDPLHHHVNPPRQPRNNFQLP
    

Molecular Weight8401.46 Da

Isoelectric Point (pI)8.23

Net Charge (pH 7.0)1.00

Net Charge (pH 7.4) 0.47

Charge Density (pH 7.0) 0.0133

GRAVY Index-0.95

Hydrophobic Moment 0.56

Boman Index-0.14

Instability Index28.30

Aliphatic Index 58.53

Aromaticity 0.0267

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3548.58

LogP -39.43

H-bond Donors 117.0

H-bond Acceptors 120.0

Rotatable Bonds 278.0

Heavy Atoms 588.0

Ring Count 16.0

Amide Bonds 83.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0265145 VERIFIED: YES

Provenance & Taxonomy

OrganismArabidopsis thaliana [Plant]

FamilyProtein CLAVATA

Tax ID3702

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Other Mods52:Hydroxyproline; 55:Hydroxyproline; 55:O-linked (Ara...) hydroxyproline

Bio-Activity Profile

Function

Growth regulation Development regulation Receptor modulation Immunomodulatory ACE inhibitory

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

PaperSource-linked PubMed record(s) for Protein CLAVATA 3 (Arabidopsis thaliana): PMID 10082464##10617197##27862469##16244158##11457943##16055633##16407446##16751438##16489133##16902140##16902141##16603652##18034320##18078779##18202283##19525968##20697738##20626648##19933383##20016993 PMID10082464;10617197;27862469;16244158;11457943;16055633;16407446;16751438;16489133;16902140;16902141;16603652;18034320;18078779;18202283;19525968;20697738;20626648;19933383;20016993 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10082464/