Peptide Database

Peptide NameIndolicidin (4-13)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length10 amino acids

Chemical FormulaC83H102N22O11

DescriptionStandard

        WKWPWWPWRR
    

Molecular Weight1583.84 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.2759

GRAVY Index-2.06

Hydrophobic Moment 0.49

Boman Index-0.23

Instability Index60.52

Aliphatic Index 0.00

Aromaticity 0.5000

Extinction Coeff. Reduced 27500.00

Extinction Coeff. Oxidized 27500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 536.41

LogP 3.05

H-bond Donors 21.0

H-bond Acceptors 14.0

Rotatable Bonds 39.0

Heavy Atoms 116.0

Ring Count 12.0

Amide Bonds 9.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0066610 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetMicrococcus luteus ATCC 9341

Activity0.4 μM

MethodMIC

RECORD: Rec_0131360 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

Targethuman red blood cells

Activity100 % hemolysis at 31.3 μM

MethodHemolysis