MYP_173220
SPMI1
Anticancer
Standard
11 amino acids
C62H86N12O20
Standard
TSFSEYWSLLS
1319.41 Da
4.05
-1.60
-1.79
-0.1455
0.07
0.32
0.26
17.17
70.91
0.2727
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
528.79
-4.53
20.0
19.0
39.0
94.0
4.0
10.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0166155
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
MDM2/MDMX-binding peptide
32630
Structure & Mods
hydrocarbon-stapled side-chain cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
Acetylation
Amidation
Stapled: Ⓧ(4) and Ⓧ (8) are cross-linked by hydrocarbon stapling
Bio-Activity Profile
Anticancer
HCT116 p53+/+
>100 μM
IC50
RECORD: Rec_0412035
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
MDM2/MDMX-binding peptide
32630
Structure & Mods
hydrocarbon-stapled side-chain cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
Acetylation
Amidation
Stapled: Ⓧ(4) and Ⓧ (8) are cross-linked by hydrocarbon stapling
Bio-Activity Profile
Anticancer
HCT116 p53-/-
>100 μM
IC50