Peptide Database

Peptide NameEptifibatide

Function Ontology

Hemostasis ▸ Antithrombotic activity

Standard StatusStandard

Sequence Length7 amino acids

Chemical FormulaC33H57N15O8S

DescriptionStandard

        MPRHARG
    

Molecular Weight823.97 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)1.59

Net Charge (pH 7.4) 1.32

Charge Density (pH 7.0) 0.2268

GRAVY Index-1.50

Hydrophobic Moment 0.71

Boman Index-0.51

Instability Index75.96

Aliphatic Index 14.29

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 381.61

LogP -4.29

H-bond Donors 14.0

H-bond Acceptors 12.0

Rotatable Bonds 25.0

Heavy Atoms 57.0

Ring Count 2.0

Amide Bonds 6.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0168272 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermMpr=mercaptopropionyl

C-TermAmidation

Bio-Activity Profile

Function

Antithrombotic

MethodHPLC

Half-LifeIntravenous injection to Human, in vitro; 4068 s