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MYP_173175
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Basic Information
Angiotensin I-converting enzyme inhibitor WV
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Xanthine oxidase inhibition
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Therapeutic / Biomedical activity ▸ Dermatology / Cosmetic bioactivity ▸ Skin aging modulation ▸ Anti-aging
Standard
2 amino acids
C16H21N3O3
Standard
Sequence
WV
Physicochemical Analysis
303.36 Da
5.53
-0.24
-0.44
-0.1200
1.65
0.62
0.94
-37.45
145.00
0.5000
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
108.21
1.26
4.0
3.0
6.0
22.0
2.0
1.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0315233 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Designed peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
RECORD: Rec_0361608 VERIFIED: NO
Provenance & Taxonomy
Apis mellifera [Animal]
Dipeptide
7460
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-aging Antioxidant
Human monocytic leukemia cell line U3-1 (In vitro)
Cell viability assay; Antioxidant assay
RECORD: Rec_0375720 VERIFIED: YES
Provenance & Taxonomy
unidentified [other]
Angiotensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory DPP-IV Inhibitory
Dipeptidyl peptidase IV
65.69 ± 2.95 μM
IC50
RECORD: Rec_0417867 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
alpha-Lactalbumin-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
DPP-IV inhibitory Antidiabetic
Dipeptidyl peptidase-IV (DPP-IV)
65.69 μM
IC50
PaperDipeptidyl peptidase IV inhibitory and antioxidative properties of milk protein-derived dipeptides and hydrolysates | Nongonierma, A. et al. | DOI: 10.1016/j.peptides.2012.11.016 Evidence URLhttps://www.uniprot.org/uniprotkb/P00711/entry
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