Peptide Database

Peptide NameP-25

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC103H165N39O17S

DescriptionStandard

        KRIGWRWRRWPRLRCK
    

Molecular Weight2253.73 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)7.75

Net Charge (pH 7.4) 7.53

Charge Density (pH 7.0) 0.4843

GRAVY Index-1.79

Hydrophobic Moment 0.82

Boman Index-0.78

Instability Index152.19

Aliphatic Index 48.75

Aromaticity 0.1875

Extinction Coeff. Reduced 16500.00

Extinction Coeff. Oxidized 16500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 961.84

LogP -5.16

H-bond Donors 40.0

H-bond Acceptors 26.0

Rotatable Bonds 73.0

Heavy Atoms 160.0

Ring Count 7.0

Amide Bonds 15.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0085329 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus

Activity4 μg/mL

MethodMIC

RECORD: Rec_0137189 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetBacillus subtilis

Activity4 μg/mL

MethodMIC

RECORD: Rec_0247499 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hemolytic

Targethuman RBCs

Activity2.1 μg/mL

MethodLC50

RECORD: Rec_0291542 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli

Activity8 μg/mL

MethodMIC