Peptide Database

Peptide NameCorticotropin-like intermediate lobe peptide

Function Ontology

Antimicrobial

Cardiovascular

Hormonal / Endocrine ▸ Hormone peptide

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length22 amino acids

Chemical FormulaC115H172N28O35

DescriptionStandard

        RPVKVYPNVAENESAEAFPLEF
    

Molecular Weight2506.76 Da

Isoelectric Point (pI)4.49

Net Charge (pH 7.0)-2.23

Net Charge (pH 7.4) -2.44

Charge Density (pH 7.0) -0.1014

GRAVY Index-0.40

Hydrophobic Moment 0.58

Boman Index0.02

Instability Index41.58

Aliphatic Index 70.91

Aromaticity 0.1364

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1011.81

LogP -7.80

H-bond Donors 32.0

H-bond Acceptors 33.0

Rotatable Bonds 76.0

Heavy Atoms 178.0

Ring Count 6.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0151615 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyCorticotropin-like intermediate lobe peptide

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Other Mods14:Phosphoserine; 12:N-linked (GlcNAc...) asparagine

Bio-Activity Profile

Function

Antimicrobial Hormone Endocrine Neuropeptide Neuromodulator Cardiovascular Metabolic regulation Physiological regulation Receptor modulation Immunomodulatory

Half-LifeMammalian: 1 hour; Yeast: 2 min; E. coli: 2 min

RECORD: Rec_0287557 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyOpioid

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Opioid Analgesic Neuromodulator

RECORD: Rec_0368866 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]; Rattus norvegicus [Animal]

Tax ID10090, 10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide