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MYP_173108
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Basic Information
SA-35
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Anti-Pneumovirus ▸ Anti-RSV
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
20 amino acids
C107H182N36O26S2
Standard
Sequence
MITHGCYTRTRHKHKLKKTL
Physicochemical Analysis
2452.95 Da
10.58
5.75
5.36
0.2873
-1.11
0.48
-0.36
24.89
58.50
0.0500
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1031.29
-9.53
40.0
37.0
85.0
171.0
4.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0003129 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Respiratory syncytial virus (RSV)
PMID32124885 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32124885/
RECORD: Rec_0174701 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
PMID32124885 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32124885/
RECORD: Rec_0310475 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
MA-104 cells:CC50= 2
PMID32124885 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32124885/
RECORD: Rec_0336652 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-RSV Fusion inhibition
Respiratory syncytial virus (RSV)
1000 μg/mL
Mammalian: 30 h; Yeast: >20 h; E. coli: >10 h
PaperLinear and dendrimeric antiviral peptides: design, chemical synthesis and activity against human respiratory syncytial virus. | Kozhikhova KV, Shilovskiy IP, Shatilov AA, Timofeeva AV, Turetskiy EA, Vishniakova LI, Nikolskii AA, Barvinskaya ED, Karthikeyan S, Smirnov VV, Kudlay DA, Andreev SM, Khaitov MR | J Mater Chem B. 2020 Apr 1;8(13):2607-2617 | DOI:10.1039/c9tb02485a | PMID:32124885 PMID32124885 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32124885/