Peptide Database

Peptide NameDefensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length98 amino acids

Chemical FormulaC472H725N133O141S7

DescriptionStandard

        MRTFLVTFVLVVVVGVISAYPSNPVEVEAEDFDAQDPDLQTFQDTFYEVPQVHSRQKRATCDLLSAFGVGHAACAAHCIGHGYRGGYCNSKAVCTCRR
    

Molecular Weight10743.07 Da

Isoelectric Point (pI)6.01

Net Charge (pH 7.0)-2.20

Net Charge (pH 7.4) -2.72

Charge Density (pH 7.0) -0.0224

GRAVY Index0.05

Hydrophobic Moment 0.52

Boman Index0.08

Instability Index47.48

Aliphatic Index 76.53

Aromaticity 0.1020

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4367.10

LogP -46.17

H-bond Donors 157.0

H-bond Acceptors 150.0

Rotatable Bonds 341.0

Heavy Atoms 753.0

Ring Count 18.0

Amide Bonds 104.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0246938 VERIFIED: YES

Provenance & Taxonomy

OrganismPhlebotomus duboscqi [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Antifungal Anti-Candida Antiparasitic Anti-Yeast Non-hemolytic

TargetNo Target Organism Found