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MYP_173079
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Basic Information
LTX-302
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
9 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
WKKWXKKWK
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0323596 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Dip = diphenylalanine
Bio-Activity Profile
Anticancer Cytotoxic
HT-29
75±5 μM
IC50
PMID21453492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21453492/
RECORD: Rec_0352311 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
X=Dip (Diphenylalanine)
Bio-Activity Profile
Antimicrobial Anticancer
K562
8.2±1.3 μM
IC50
PaperPubMed PMID: 21453492 PMID21453492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21453492/
RECORD: Rec_0364049 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
X=Dip (Diphenylalanine)
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
HUVEC
123±9 μM
IC50
PaperPubMed PMID: 21453492 PMID21453492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21453492/
RECORD: Rec_0400141 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
X=Dip (Diphenylalanine)
Bio-Activity Profile
Antimicrobial Anticancer
HL-60/ADR
10.5±3.1 μM
IC50
PaperPubMed PMID: 21453492 PMID21453492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21453492/
RECORD: Rec_0401150 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
X=Dip (Diphenylalanine)
Bio-Activity Profile
Antimicrobial Anticancer
HL-60
8±1.1 μM
IC50
PaperPubMed PMID: 21453492 PMID21453492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21453492/
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