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MYP_173079
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Basic Information
LTX-302
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
9 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
WKKWXKKWK
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0224566 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
X=Dip (Diphenylalanine)
Bio-Activity Profile
Antimicrobial Anticancer
K562/Gleevec
9±2.1 μM
IC50
PaperPubMed PMID: 21453492 PMID21453492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21453492/
RECORD: Rec_0272176 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
X=Dip (Diphenylalanine)
Bio-Activity Profile
Antimicrobial Anticancer
A20
16±3 μM
IC50
PaperPubMed PMID: 21453492 PMID21453492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21453492/
RECORD: Rec_0282595 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
X=Dip (Diphenylalanine)
Bio-Activity Profile
Antimicrobial Anticancer
MT-1
73±2 μM
IC50
PaperPubMed PMID: 21453492 PMID21453492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21453492/
RECORD: Rec_0301028 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 55.6%, E 0.0%, T 22.2%, C 22.2% [Linear]
residue-level stereochemical modification [Mixed]
None
Amidation
Dip = diphenylalanine
Bio-Activity Profile
Anticancer Antimicrobial
PaperCancerPPD: a database of anticancer peptides and proteins PMID25270878 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25270878/
RECORD: Rec_0302011 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Dip = diphenylalanine
Bio-Activity Profile
Anticancer Cytotoxic
MT-1
73±2 μM
IC50
PMID21453492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21453492/
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