Peptide Database

Peptide NameBeta-defensin 37

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length63 amino acids

Chemical FormulaC325H516N84O83S9

DescriptionStandard

        MKISCFLLLVLSLSCFQINPFAVLDTRVCIEKRNTCHILQCPLFRDVVGTCFEGIGKCCHKYF
    

Molecular Weight7216.67 Da

Isoelectric Point (pI)8.49

Net Charge (pH 7.0)2.60

Net Charge (pH 7.4) 2.15

Charge Density (pH 7.0) 0.0412

GRAVY Index0.65

Hydrophobic Moment 0.54

Boman Index0.19

Instability Index57.60

Aliphatic Index 105.08

Aromaticity 0.1111

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2660.25

LogP -18.82

H-bond Donors 100.0

H-bond Acceptors 97.0

Rotatable Bonds 237.0

Heavy Atoms 501.0

Ring Count 11.0

Amide Bonds 66.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0168504 VERIFIED: NO

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyDefensin

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

PaperCross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract PMID16033865 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16033865/; https://www.uniprot.org/uniprotkb/Q32ZF9/entry; https://bblserver.org.in/ampdb/

RECORD: Rec_0192065 VERIFIED: YES