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MYP_173001
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Basic Information
17
Anticancer
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
not Standard
5 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
YXGFM
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0133211 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
None
None
X=Cα -dialkylated glycine (Aaa2)
Bio-Activity Profile
Antimicrobial Anticancer
26.4 %
Inhibition
PaperTumor-cell-targeted methionine-enkephalin analogues containing unnatural amino acids: design, synthesis, and in vitro antitumor activity. J Med Chem. 2006 Jun 1;49(11):3136-42. doi: 10.1021/jm051026+. PMID: 16722632. PMID16722632 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16722632/
RECORD: Rec_0135945 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
None
None
X=Cα -dialkylated glycine (Aaa2)
Bio-Activity Profile
Antimicrobial Anticancer
PaperTumor-cell-targeted methionine-enkephalin analogues containing unnatural amino acids: design, synthesis, and in vitro antitumor activity. J Med Chem. 2006 Jun 1;49(11):3136-42. doi: 10.1021/jm051026+. PMID: 16722632. PMID16722632 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16722632/
RECORD: Rec_0136514 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
None
None
X=Cα -dialkylated glycine (Aaa2,2 )
Bio-Activity Profile
Antimicrobial Anticancer
HT-29
3.3 %
Inhibition
PaperTumor-cell-targeted methionine-enkephalin analogues containing unnatural amino acids: design, synthesis, and in vitro antitumor activity. J Med Chem. 2006 Jun 1;49(11):3136-42. doi: 10.1021/jm051026+. PMID: 16722632. PMID16722632 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16722632/
RECORD: Rec_0140958 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
None
None
X=Cαα -dialkylated glycine (Aaa1 )
Bio-Activity Profile
Antimicrobial Anticancer
HEp-2
1 %
Inhibition
PaperTumor-cell-targeted methionine-enkephalin analogues containing unnatural amino acids: design, synthesis, and in vitro antitumor activity. J Med Chem. 2006 Jun 1;49(11):3136-42. doi: 10.1021/jm051026+. PMID: 16722632. PMID16722632 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16722632/
RECORD: Rec_0147623 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
None
None
X=Cαα -dialkylated glycine (Aaa1 )
Bio-Activity Profile
Antimicrobial Anticancer
HeLa
8.5 %
Inhibition
PaperTumor-cell-targeted methionine-enkephalin analogues containing unnatural amino acids: design, synthesis, and in vitro antitumor activity. J Med Chem. 2006 Jun 1;49(11):3136-42. doi: 10.1021/jm051026+. PMID: 16722632. PMID16722632 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16722632/
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