Peptide Database

Peptide NameUnnamed

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor

Standard StatusStandard

Sequence Length5 amino acids

Chemical FormulaC27H51N7O6

DescriptionStandard

        VPKVK
    

Molecular Weight569.74 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)1.73

Net Charge (pH 7.4) 1.52

Charge Density (pH 7.0) 0.3464

GRAVY Index-0.20

Hydrophobic Moment 0.45

Boman Index-0.14

Instability Index23.78

Aliphatic Index 116.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 222.97

LogP -0.59

H-bond Donors 7.0

H-bond Acceptors 8.0

Rotatable Bonds 18.0

Heavy Atoms 40.0

Ring Count 1.0

Amide Bonds 4.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0294242 VERIFIED: NO

Provenance & Taxonomy

OrganismOvis aries [Animal]

FamilyACE-inhibitory peptide

Tax ID9940

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antihypertensive ACE inhibitory

TargetACE

Activity93.7 μM

MethodIC50

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