‹ ›
MYP_172980
← PREVIOUS NEXT → BACK
Basic Information
Nisin T
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
not Standard
34 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
IXAIXLAXPGAKXGALMGANMTXAXANASIHVXK
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0013206 VERIFIED: YES
Provenance & Taxonomy
Lactococcus lactis [Bacterium]
Bacteriocin
1358
Structure & Mods
lanthionine-constrained cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
Dha= Didehydroalanine, Dhb= Didehydroaminobutyric acid, Abu= 2-aminobutyric acid, Lanthionine (Ala-S-Ala) formation from 3-7 Ala, and β-methyllanthionine (Abu-S-Ala) from 8-11, 13-19, 23-26, 25-28 in between Abu and Ala
Bio-Activity Profile
Antimicrobial Antimycobacterial Antibacterial
Mycobacterium avium subsp. Hominissuis (CIT05/03)
MIC
PMID21468208 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21468208/
RECORD: Rec_0029226 VERIFIED: YES
Provenance & Taxonomy
Lactococcus lactis [Bacterium]
Bacteriocin
1358
Structure & Mods
lanthionine-constrained cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
Dha= Didehydroalanine, Dhb= Didehydroaminobutyric acid, Abu= 2-aminobutyric acid, Lanthionine (Ala-S-Ala) formation from 3-7 Ala, and β-methyllanthionine (Abu-S-Ala) from 8-11, 13-19, 23-26, 25-28 in between Abu and Ala
Bio-Activity Profile
Antimicrobial Antimycobacterial Antibacterial
Mycobacterium tuberculosis H37Ra
MIC
PMID21468208 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21468208/
RECORD: Rec_0079876 VERIFIED: YES
Provenance & Taxonomy
Lactococcus lactis [Bacterium]
Bacteriocin
1358
Structure & Mods
lanthionine-constrained cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
Dha= Didehydroalanine, Dhb= Didehydroaminobutyric acid, Abu= 2-aminobutyric acid, Lanthionine (Ala-S-Ala) formation from 3-7 Ala, and β-methyllanthionine (Abu-S-Ala) from 8-11, 13-19, 23-26, 25-28 in between Abu and Ala
Bio-Activity Profile
Antimicrobial Antimycobacterial Antibacterial
Mycobacterium avium paratuberculosis (ATCC 19698)
MIC
PMID21468208 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21468208/
RECORD: Rec_0337951 VERIFIED: YES
Provenance & Taxonomy
Lactococcus lactis [Bacterium]
Bacteriocin
1358
Structure & Mods
lanthionine-constrained cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
Dha= Didehydroalanine, Dhb= Didehydroaminobutyric acid, Abu= 2-aminobutyric acid, Lanthionine (Ala-S-Ala) formation from 3-7 Ala, and β-methyllanthionine (Abu-S-Ala) from 8-11, 13-19, 23-26, 25-28 in between Abu and Ala
Bio-Activity Profile
Antimicrobial Antimycobacterial Antibacterial
Mycobacterium kansasii CIT11/06
MIC
PMID21468208 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21468208/
RECORD: Rec_0392417 VERIFIED: YES
Provenance & Taxonomy
Lactococcus lactis [Bacterium]
Bacteriocin
1358
Structure & Mods
lanthionine-constrained cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
Dha= Didehydroalanine, Dhb= Didehydroaminobutyric acid, Abu= 2-aminobutyric acid, Lanthionine (Ala-S-Ala) formation from 3-7 Ala, and β-methyllanthionine (Abu-S-Ala) from 8-11, 13-19, 23-26, 25-28 in between Abu and Ala
Bio-Activity Profile
Antimicrobial Antimycobacterial Antibacterial
Mycobacterium smegmatis MC2155
PMID21468208 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21468208/