Peptide Database

Peptide Namenatriuretic peptide NsNP-b

Function Ontology

Antimicrobial

Cardiovascular

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length39 amino acids

Chemical FormulaC154H255N45O53S3

DescriptionStandard

        SGSKTAKIGDGCFGLPLDRIGSTSGMGCGSVPKPTPGGS
    

Molecular Weight3681.14 Da

Isoelectric Point (pI)8.84

Net Charge (pH 7.0)1.44

Net Charge (pH 7.4) 1.20

Charge Density (pH 7.0) 0.0369

GRAVY Index-0.21

Hydrophobic Moment 0.46

Boman Index0.11

Instability Index16.74

Aliphatic Index 50.00

Aromaticity 0.0256

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1530.59

LogP -24.43

H-bond Donors 55.0

H-bond Acceptors 58.0

Rotatable Bonds 118.0

Heavy Atoms 255.0

Ring Count 5.0

Amide Bonds 38.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0114218 VERIFIED: YES

Provenance & Taxonomy

OrganismNotechis scutatus scutatus [Animal]

Familynatriuretic peptide NsNP

Tax ID70142

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide12-28

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Receptor modulation

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0210077 VERIFIED: NO