Peptide Database

Peptide NameSyn-xiamencin-44

Function Ontology

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Venom / Toxin ▸ General toxin ▸ Toxicity

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC143H227N41O32

DescriptionStandard

        AGRQALWKYLLEELRKRGKKAFIAW
    

Molecular Weight3032.59 Da

Isoelectric Point (pI)10.55

Net Charge (pH 7.0)4.80

Net Charge (pH 7.4) 4.60

Charge Density (pH 7.0) 0.1919

GRAVY Index-0.55

Hydrophobic Moment 0.68

Boman Index-0.15

Instability Index53.77

Aliphatic Index 94.00

Aromaticity 0.1600

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1221.00

LogP -5.45

H-bond Donors 45.0

H-bond Acceptors 37.0

Rotatable Bonds 104.0

Heavy Atoms 216.0

Ring Count 6.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0099714 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiparasitic

TargetL. donovani

Activity1.18 μM

MethodIC50

RECORD: Rec_0360175 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiparasitic Toxicity

TargetTHP-1 cells

Activity<20 μM

MethodCC50