Peptide Database

Peptide NameGlucagon

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC154H224N42O51S

DescriptionStandard

        HSEGTFSNDYSKYLETRRAQDFVEWLMNS
    

Molecular Weight3511.74 Da

Isoelectric Point (pI)4.90

Net Charge (pH 7.0)-2.15

Net Charge (pH 7.4) -2.41

Charge Density (pH 7.0) -0.0740

GRAVY Index-1.09

Hydrophobic Moment 0.65

Boman Index-0.19

Instability Index40.49

Aliphatic Index 40.34

Aromaticity 0.1724

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1550.02

LogP -16.86

H-bond Donors 55.0

H-bond Acceptors 51.0

Rotatable Bonds 115.0

Heavy Atoms 248.0

Ring Count 7.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0035469 VERIFIED: NO

Provenance & Taxonomy

OrganismCarassius auratus [Animal]

FamilyGlucagon

Tax ID7957

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 3.5 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0195174 VERIFIED: NO

Provenance & Taxonomy

OrganismCarassius auratus [Animal]

FamilyGlucagon

Tax ID7957

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic

RECORD: Rec_0320936 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/