Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length456 amino acids

Chemical FormulaC2314H3657N619O648S10

DescriptionStandard

        TNPGFMVRITQAGLDYAHEQGIAILEKELAQLKLPDISGDSRVLRVGKVHYELSRLRLRDFYLPYSRITPISNVGLQVSISNAFAELDGDWRVKFLIIQDHGSFNLKVENVYIKIILRLGSDTIGKPTISTSECNARISKVRVLFSGRLAWLYNLFHSVIESRLRKSLEHKVCDNVAKSVQNELQKYIQTLPVTAKIDNKTGIDYSLVAPPRATAQSLDADLKGEFYSLGHRSTVPFSPLPLAFPSDHERMVYFGASSYFFNTAGIAYHKAGALVFEITEATIPKDAGFKLDTSVFSAFIPQLEEMYPNMPMKFRLSAPTAPFLTIGPEGISFQPIVDAQAYAILPNSSLAPLFLLSLVRNVSAVINVRSGHIVGSLDVGRIRLSLKDSAVGTFQVRMMQSLMNVLTSNVLLPRFNARLDEGFPLPLLDRIQLSNILVRFHQNFLLLGADVHFQPQ
    

Molecular Weight50837.20 Da

Isoelectric Point (pI)9.21

Net Charge (pH 7.0)7.38

Net Charge (pH 7.4) 6.51

Charge Density (pH 7.0) 0.0162

GRAVY Index0.07

Hydrophobic Moment 0.66

Boman Index0.10

Instability Index36.57

Aliphatic Index 104.98

Aromaticity 0.0943

Extinction Coeff. Reduced 31860.00

Extinction Coeff. Oxidized 31985.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0380286 VERIFIED: NO

Provenance & Taxonomy

OrganismAegithalos caudatus (Long-tailed tit) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria