Peptide Database

Peptide NameDybowskin-5 (Frogs, amphibians, animals)

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length38 amino acids

Chemical FormulaC168H293N47O48S2

DescriptionStandard

        GLFSVVTGVLKAVGKNVAKNVGGSLLEQLKCKKISGGC
    

Molecular Weight3803.54 Da

Isoelectric Point (pI)9.79

Net Charge (pH 7.0)4.74

Net Charge (pH 7.4) 4.49

Charge Density (pH 7.0) 0.1247

GRAVY Index0.44

Hydrophobic Moment 0.60

Boman Index0.18

Instability Index3.43

Aliphatic Index 112.63

Aromaticity 0.0263

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1543.63

LogP -16.88

H-bond Donors 55.0

H-bond Acceptors 55.0

Rotatable Bonds 135.0

Heavy Atoms 265.0

Ring Count 1.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0417581 VERIFIED: YES

Provenance & Taxonomy

OrganismRana dybowskii [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide31-38

Bio-Activity Profile

Function

Antimicrobial Antifungal

TargetMicrococcus luteus

Activity1.8 μM

MethodMIC

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