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MYP_172801
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Basic Information
R2PLx-22
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
22 amino acids
C102H181N29O31S
Standard
Sequence
GIMDTVKNAAKNLAGQLLDKLK
Physicochemical Analysis
2341.77 Da
9.53
1.76
1.55
0.0799
-0.15
0.64
-0.00
-14.03
115.45
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1002.60
-9.60
33.0
34.0
85.0
163.0
0.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0315123 VERIFIED: YES
Provenance & Taxonomy
skin secretions of the pickerel frog [Animal]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
U-251MG
104.1 μM
IC50
PaperPubMed PMID: 30279210 PMID30279210 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30279210/
RECORD: Rec_0328626 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Enterococcus faecalis(NCTC 12697)
512 μM
MIC
PMID30279210 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30279210/
RECORD: Rec_0329749 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa(ATCC 27853)
MIC
PMID30279210 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30279210/
RECORD: Rec_0396148 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
256 μM
MIC
PMID30279210 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30279210/
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