Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length395 amino acids

Chemical FormulaC1942H3107N519O557S12

DescriptionStandard

        VDFCYQLFFDLIKCLPLVALIAAAFSANPGVKIRLTQKGLEYGRQLGVASLLEKLKTAQIPDFSGKERVSPIGKVQYSLTNIHIVNLGLPQSSINLVPGSGVQLSISNAFINLRGNWRVKYLRIIKDSGSLDVNVNGLSISQTIAIKSDATGKPEASSAACSASVSSAKVKFHGGASWLYNLFSKFIDKALRKALEKQMCPLVAKSIADLNPRLKTLNVLAKVDKYAEIEYSMVSSPQISQPAIDLNLKGEFYNIGRHQEAPFPAPAFSLPAQSSNMIYIALSSFTPNSAGFVYNNAGVLSMYVTDDMIPRSSPIRLSTSTFGFFIPQVTMRSRPSMLVKADKNPVVKFQPNVMTVDATATATAYAIQPNGTLSPLFVLNVVSQRARKDFRDKKN
    

Molecular Weight43022.37 Da

Isoelectric Point (pI)9.76

Net Charge (pH 7.0)18.96

Net Charge (pH 7.4) 18.45

Charge Density (pH 7.0) 0.0480

GRAVY Index0.04

Hydrophobic Moment 0.85

Boman Index0.09

Instability Index37.31

Aliphatic Index 96.56

Aromaticity 0.0861

Extinction Coeff. Reduced 28880.00

Extinction Coeff. Oxidized 29130.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0345444 VERIFIED: NO

Provenance & Taxonomy

OrganismOryzias sinensis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria

MethodQualitative functional evidence