Peptide Database

Peptide NameBeta-defensin 39

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC375H604N112O106S7

DescriptionStandard

        MNNTVSQIRGYWLFQLREQLGVSGIDSVKCFQKNNTCHTIRCPYFQDEVGTCYEGRGKCCQKRLLSIRVPKKKV
    

Molecular Weight8601.95 Da

Isoelectric Point (pI)9.50

Net Charge (pH 7.0)7.53

Net Charge (pH 7.4) 7.15

Charge Density (pH 7.0) 0.1017

GRAVY Index-0.53

Hydrophobic Moment 0.48

Boman Index-0.15

Instability Index22.24

Aliphatic Index 70.95

Aromaticity 0.0946

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3607.98

LogP -37.85

H-bond Donors 132.0

H-bond Acceptors 122.0

Rotatable Bonds 293.0

Heavy Atoms 600.0

Ring Count 11.0

Amide Bonds 83.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0030317 VERIFIED: NO

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyDefensin

Tax ID10116

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal